If you notice other effects not listed above, contact your doctor or pharmacist. Otherwise, call a poison control center right away. US: Food and Drug Administration has approved Bempedoic acid (NEXLETOL)—a once-daily, oral non-statin treatment for adults with heterozygous familial hypercholesterolemia (HeFH) or established atherosclerotic cardiovascular disease (ASCVD), as an adjunct to diet and maximally tolerated statin therapy. NEXLETOL is a prescription medicine used along with diet and other lipid-lowering medicines in the treatment of adults with: heterozygous familial hypercholesterolemia (HeFH). Remember to use it at the same time each day. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Canada residents can call a provincial poison control center. Last updated on Feb 29, 2020. The most common side effects include hyperuricemia (high blood levels of uric acid), pain in arms or legs, and anemia (low red blood cell counts).. Bempedoic acid blocks an enzyme in the liver called adenosine … NEXLETOL Savings, Coupons and Information. Avoid concomitant use of Nexletol with simvastatin (greater than 20 mg) and with pravastatin (greater than 40 mg). It is not known if Nexletol passes into your breast milk. Consult your doctor for more details. Nexletol is a brand-name prescription drug. tablet coating: partially hydrolyzed polyvinyl alcohol, polyethylene glycol, talc, and titanium dioxide. Should I avoid certain foods while taking Nexletol 180 Mg Tablet Antihyperlipidemic - ATP-Citrate Lyase (ACLY) Inhibitor? If you have any questions, ask your doctor or pharmacist. Find everything you need to know about Bempedoic Acid (Nexletol), including what it is used for, warnings, reviews, side effects, and interactions. Keep Nexletol and all medicines out of the reach of children. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. If you take too much Nexletol, call your poison control center at 1-800-222-1222 or go to the nearest hospital emergency room right away. Keep the desiccant packet in the bottle. Nexletol 180 Mg Tablet Antihyperlipidemic - ATP-Citrate Lyase (ACLY) Inhibitor, Enter your medication into the WebMD interaction checker, heterozygous inherited high blood cholesterol, hardening of the arteries due to plaque buildup, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, List Nexletol 180 Mg Tablet Antihyperlipidemic - ATP-Citrate Lyase (ACLY) Inhibitor side effects by likelihood and severity. You may report side effects to Health Canada at 1-866-234-2345. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The FDA has approved two new non-statin drugs that clinical trials indicated can help reduce high cholesterol. You may take Nexletol with or without food. Select one or more newsletters to continue. Statins have been and continue to be the go-to treatment choice for high cholesterol because of how well they work to lower cholesterol and prevent heart disease and death. The risk of getting tendon problems while you take Nexletol is higher if you: are taking antibiotics (fluoroquinolones). Learn more about Bempedoic Acid (Nexletol… U.S. regulators on Friday approved a new type of cholesterol-lowering drug aimed at millions of people who can't tolerate — or don't get enough help from — widely used statin pills like Lipitor and Crestor. Do not double the dose to catch up. If it is near the time of the next dose, skip the missed dose. Available for Android and iOS devices. Last month, a new kind of medication called bempedoic acid (Nexletol) was approved for use by the FDA as a novel way to lower cholesterol. are breastfeeding or plan to breastfeed. Before taking bempedoic acid, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Taking simvastatin or pravastatin with Nexletol may increase your risk of developing muscle pain or weakness (myopathy). Store in original container at room temperature away from light and moisture. known heart disease who need additional lowering of “bad” cholesterol (LDL-C) levels. It may take up to 12 weeks before you get the full benefit of this drug. If you become pregnant, talk to your doctor right away about the risks and benefits of this medication. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Consult your doctor before breast-feeding. Tell your doctor right away if you have any serious side effects, including: toe/joint pain, difficulty urinating (for example, due to enlarged prostate). Before using this medication, tell your doctor or pharmacist your medical history, especially of: liver disease, kidney disease, gout, tendon problems. NEXLETOL and NEXLIZET are indicated as adjuncts to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of LDL-C. Lowering "bad" cholesterol may help to decrease the risk of heart disease and help prevent strokes and heart attacks. It may harm them. Take your next dose at the regular time. In Canada - Call your doctor for medical advice about side effects. For more information, ask your healthcare provider or pharmacist. Nexletol is a daily pill approved for people with a genetic predisposition for high cholesterol and for heart disease patients who need to further reduce their bad cholesterol. Bempedoic acid is used along with a proper diet and other medications to help lower "bad" cholesterol (such as LDL) in the blood. Many people using this medication do not have serious side effects. You should not become pregnant while using bempedoic acid. NEXLETOL is an adenosine triphosphate-citrate lyase (ACL) inhibitor indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of LDL-C. are pregnant. Do not store in the bathroom. Tell your doctor if you are pregnant or plan to become pregnant. You and your healthcare provider will decide if you should take Nexletol while you are pregnant. symptoms of the common cold, flu, or flu-like symptoms, Store Nexletol in the original package at room temperature between 68ºF to 77ºF (20ºC to. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Abdominal pain may occur. Properly discard this product when it is expired or no longer needed. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine. Consult your doctor for more details. severe foot pain especially in the toe joint. It is very important to continue to follow your doctor's advice about diet and exercise. The NEXLETOL & NEXLIZET Co-Pay Card may not be sold, purchased, traded, or offered for sale, purchase, or trade. It is used with other cholesterol-lowering drugs. Nexletol is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of LDL-C. It may be covered by your Medicare or insurance plan, but some pharmacy coupons or cash prices could help offset the cost. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Keep all medical and lab appointments. Take Nexletol exactly as your healthcare provider tells you to take it. It works by reducing the amount of … The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This document does not contain all possible drug interactions. Nexletol (bempedoic acid) is used to lower the level of cholesterol in the blood. Most people with high cholesterol do not feel sick. Any special considerations for special populations? It is unknown if this medication passes into breast milk. heterozygous familial hypercholesterolemia (HeFH). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Before you start taking Nexletol, tell your healthcare provider about all your medical conditions, including if you: Nexletol may affect the way other medicines work, and other medicines may affect how Nexletol works. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Do not give Nexletol to other people, even if they have the same symptoms that you have. Medically reviewed by Judith Stewart, BPharm. Nexletol, also known as bempedoic acid, should be available in late March, the company said. Older adults may be more sensitive to the side effects of this drug, especially tendon problems. Take this medication by mouth with or without food as directed by your doctor, usually once daily. Talk to your healthcare provider about the risk of tendon rupture with continued use of Nexletol. NEXLETOL and NEXLIZET are indicated as adjuncts to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease who require additional lowering of LDL-C. Bempedoic acid may harm an unborn baby. NEXLIZET is a prescription medicine that contains 2 cholesterol-lowering medicines, bempedoic acid and ezetimibe. If you miss a dose, take it as soon as you remember. Use of this NEXLETOL & NEXLIZET Co-Pay Card must be consistent with all relevant health insurance requirements and payer agreements. Nexletol also can be used for patients who are taking statins but still are having trouble lowering their LDL cholesterol. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.